While obesity confers serious health concerns and increased all-cause mortality, the vast majority of deaths are due to cardiovascular causes such as ischemic heart disease and stroke. Researcher prospectively followed 208 overweight or obese patients (BMI ?25 kg/m2) receiving medical/dietary (48 percent) or bariatric surgical (52 percent) weight loss treatment during a period of approximately one year. They measured plasma metabolic parameters and vascular endothelial function using ultrasound at baseline and following weight loss intervention, and stratified analyses by median plasma insulin levels. They found that individuals with higher baseline plasma insulin levels (above median >12 uIU/ml), who had greater than 10 percent weight loss had Garcinia Cambogia Reviews significantly improved brachial artery macro-vascular flow-mediated vasodilation and micro-vascular reactive hyperemia.
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Behavioural correlates of successful weight reduction over 3 y. Results from the Lean Habits Study
Baseline assessment took place at the start of the programme, follow-up measurements (FU) after approximately 10 weeks, after 1, 2 and 3y. Subjects were invited by mail and telephone to FU if they no longer participated in the programme. Until February 2000, a total of 6857 subjects was included in the study. Until May 2003, 1593 subjects (23.2%) attended the 3y FU. Because 10 week or 1y FU data were missing for some of these 1593 subjects, the present analyses are based on 1247 subjects with complete data.
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